Arnita Novitasari Saubig1), Meilien Himbawani2)


Background: Flat ion rebounding give beneficial impact and be also harmful to hair. This study was aimed to reveal the relation between the frequency of flat ion rebounding and the incidence of hair damage.
Methods: This was an analytical observational study with cross sectional design. The samples were 50 people who fulfilled the inclusion criteria by purposive sampling. The primary data collected as well as the hair were examined microscopically. The… Continue reading

Windy Saufia A1), Trilaksana Nugraha2)


Background: Piper betle Linn facilitate the tumor antigen initiation on immunosurveilance cells. Phylanthus niruri Linn improve the effectiveness of tumor cell of Adenocarcinoma mammae destruction. This study was aimed to prove any change of histopathological appearance of Adenocarcinoma mammae in C3H mice that give by Piper betle Linn and Phylanthus niruri Linn extracts.
Methods: This was a post-test only control group design, using 10 C3H mice that fulfilled the inclusion criteria,… Continue reading

Andrew Johan*)


Nitric Oxide (NO) is produced in higher organisms by the oxidation of one of the terminal guanido-nitrogen atoms of L-arginine. Nitric Oxide Synthase (NOS) catalyzes the oxidation of arginine to NO and citrulline. Reduced nicotinamide adenine dinucleotide phosphate (NADPH) and oxygen (O2) are required as co-substrates.
NOS exists in three distinct isoforms: 1. constitutive neuronal NOS (NOS I or nNOS), 2. inducible NOS (NOS II or iNOS), and 3. constitutive endothelial NOS (NOS III or eNOS).… Continue reading

Maria Belladona RS.1), Ratna Damma Purnawati2)


Background: Cyclea barbata L. Miers (cincau hijau) may increase tumor cells necrosis significantly, though no studies about the potential effect on skin cancer, besides the incidence rate of skin cancer is still high. This study was aimed to know the effect of C. barbata L. Miers leaves extract on the histopathology epidermal changes of C3H that exposed with carcinogen.
Methods: This was a post test only control group design study on 20 C3H… Continue reading

Atik Madiastuti1), Hermina Sukmaningtyas2)


Background: The study is to prove the effect of L- arginine on the macrophage phagocyte ability in mice which stressed by electric foot shock and Listeria monocytogenes infection. It is showed by the number of latex beads which were phagocyted by macrophage in 200 macrophage.
Methods: The study was Laboratory Experimental and using The Post Test Only Control Group Design. The 12 male Balb/C were then divided into 2 groups and received standard lab diet… Continue reading