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Ardhianto P, Sugiri, Endang-Purwaningsih, Bachtiar AB

ABSTRACT

Background: Increased homocysteine plasma levels are associated with increased thrombosis. Acute coronary syndromes (ACS) is the process of thrombosis in coronary arteries induced by atherosclerosis plaque ruptures, fissures or erosion. The purpose of this study is to analyze the relationship between increased levels of homocysteine in the blood and the area of ischemic injury in myocardium of patients with ACS.

Methods: In the frame of Cardio Metabolic Investigation (Carmetin); a cross-sectional… Continue reading

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Arlita Leniseptaria Antari, David Pakaya, Dahliatul Qosimah

INTRACELLULAR KILLING CAPACITY TO MYCOBACTERIUM TUBERCULOSIS OF MACROPHAGES WERE OBTAINED FROM PULMONARY AND HEALTHY SUBJECTS’ AT RISK FOR PULMONARY TUBERCULOSIS

ABSTRACT

Background: Macrophages are the first defense mechanism in tuberculosis. The entry of Mycobacterium tuberculosis into the host macrophages and its survival in this environment are key components of tuberculosis pathogenesis. The aims of this study was to know whether there is any difference in intracellular killing capacity of Mycobacterium tuberculosis… Continue reading

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Ariosta1), Imam Budiwiyono1), Herniah Asti Wulanjani2)

THE DIFFERENCE OF PAIN RESPONSE IN THE PATIENTS UNDERGONE BONE MARROW PUCTURE WITH AND WITHOUT MIDAZOLAM PREMEDICATION

ABSTRACT

Background: Bone marrow puncture fordisease diagnostic is performed by indication. Bone marrow puncture procedure often using midazolam premedication for avoiding pain but not all. The objectiveisto analize differentiationof pain response in BMP patients with midazolam and without premedication.

Methods: Observational analytic study with cross sectional. Sampling is performed by consecutive of 26 adult patients… Continue reading

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Eka Yudhanto

 A COMPARISON BETWEEN IMMUNOSENSORY DETECTING ECD-HER2 EXPRESSION AND IMMUNOHISTOCHEMISTRY EXAMINATION HER2 IN BREAST CARCINOMA

ABSTRACT

Background: The era of molecular biology has enabled us to have an in-depth study on cellular living process, including malignancy process. In breast cancer one of the genes widely studied is HER2 where the expression of which influences the critical prognosis of the patient. Today the gold- standard of HER2 detection using immunohistochemistry-based method. This method requires laboratory and experts… Continue reading

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Indah Lestari Vidyahayati1), Anne Handrini Dewi2), Ika Dewi Ana2)

THE EFFECT OF BONE SUBSTITUTION AND HYDROXIAPATIT (Hap) TO THE BONE REMODELLING PROCESS

ABSTRACT

Background: Tissue damage by apartness, trauma, or diseases need a restoration to repair its function in a perfect condition. Several exerts have done to find materials on tissue substitution, include developing hidroxyapatite material (HAp). HAp represent bioactive material which has ability on osteoconductive, bioactivity, and biocompatibility in bone formation process. The aim of this research… Continue reading