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Mahayu Dewi Ariani1), Farida Martyaningsih2)

THE DIFFERENCES BETWEEN URINE IODIUM OF PRELEMENTARY SCHOOL-CHILDREN IN ENDEMIC AND NON ENDEMIC IODIUM DEFICIENCY OF SIRAMPOG, BREBES

ABSTRACT

Background: Mapping result of Iodine Deficiency Disorder (IDD) from The Health Office Kabupaten Brebes describes the increasing in Total Goiter Rate (TGR) for school children in 2004. The highest TGR was in Kecamatan Sirampog (40.71 %), whereas high endemic rate was 30%. This region lies on mountainous and tend to have avalanche which is a risk factor of IDD. Urinary Excretion Iodine (UEI) is the most useful marker for IDD. This is the better and simple method for iodium detection because 90% iodium excreted to urine from the body. The objectives of this study was to analyze the differences between endemic and non endemic IDD for the UEI of elementary students in Kecamatan Sirampog, Brebes.

Methods: This research has a cross-sectional design. There two groups of subjects for endemic and non endemic samples. Samples were measured for the Urinary Excretion Iodine (UEI). The measurement of UEI was taken from urine  using Ceric Ammonium Persulfate methods in Laboratory of IDD, Faculty of Medicine, University of Diponegoro, Semarang. The data was analyze using SPSS 11.5 for Windows.

Results : Mean of UEI level in endemic IDD region was 161,1 µg/L (SD± 73.9) compared to mean of UEI level in non-endemic IDD region was 245.8 µg/L (SD± 72.2). There was significant difference between two groups (p=0.01).

Conclusion: There was a significant difference of UEI level between endemic and non-endemic IDD

Keywords: UEI concentration, Iodine Deficiency Disorders (IDD) region, endemic

ABSTRAK

Latar belakang: Hasil pemetaan Gangguan Akibat Kekurangan Iodium (GAKI) yang dilakukan oleh Dinas Kesehatan Kabupaten Brebes pada tahun 2004 untuk anak sekolah, diperoleh data Total Goiter Rate (TGR) yang semakin meningkat dengan nilai TGR tertinggi ada di Kecamatan Sirampog yakni 40,71% (endemik berat 30%),berada di daerah pegunungan dan rawan longsor yang merupakan faktor resiko GAKI. Urinary Excretion Iodine (UEI) paling banyak digunakan sebagai marker biokimia untuk GAKI dibandingkan TGR karena lebih obyektif, sederhana, murah dan lebih dari 90% iodium akan diekskresi oleh tubuh lewat urin sehingga dapat merefleksikan asupan iodium pada saat itu. Penelitian ini bertujuan untuk menganalisis perbedaan kadar UEI pada anak SD di daerah endemik dan non endemik GAKI di kecamatan Sirampog Kabupaten Brebes.

Metode: Penelitian ini menggunakan design cross sectional. Subyek dibagi menjadi dua kelompok, yaitu sampel anak Sekolah Dasar daerah endemik dan daerah non endemik. Kadar iodium (UEI) dalam urin diperiksa dengan metode Ceric Ammonium Persulfate di Laboratorium GAKI FK UNDIP yang berasal dari urin sewaktu. Data diolah menggunakan SPSS 11,5 for Windows.

Hasil :  Rerata kadar UEI di daerah GAKI 161,1 µg/L (SD 73,9) dibandingkan dengan rerata kadar UEI di daerah endemik GAKI 245,8 µg/L (SD 72,2) (p=0,01).

Simpulan: Terdapat perbedaan bermakna antara kadar UEI di daerah endemik dan non endemik GAKI.

Kata Kunci: kadar UEI, Gangguan akibat kekurangan yodium (GAKI), endemik.

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